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EPS8 Inhibition Increases Cisplatin Sensitivity in Lung Cancer Cells
Cisplatin, a commonly used chemotherapeutic, is associated with ototoxicity, renal toxicity and neurotoxicity, thus identifying means to increase the therapeutic index of cisplatin may allow for improved outcomes. A SNP (rs4343077) within EPS8, discovered through a genome wide association study of c...
Autores principales: | Gorsic, Lidija K., Stark, Amy L., Wheeler, Heather E., Wong, Shan S., Im, Hae K., Dolan, M. Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868552/ https://www.ncbi.nlm.nih.gov/pubmed/24367505 http://dx.doi.org/10.1371/journal.pone.0082220 |
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