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APOBEC3G Oligomerization Is Associated with the Inhibition of Both Alu and LINE-1 Retrotransposition

Alu and LINE-1 (L1), which constitute ~11% and ~17% of the human genome, respectively, are transposable non-LTR retroelements. They transpose not only in germ cells but also in somatic cells, occasionally causing cancer. We have previously demonstrated that antiretroviral restriction factors, human...

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Detalles Bibliográficos
Autores principales: Koyama, Takayoshi, Arias, Juan Fernando, Iwabu, Yukie, Yokoyama, Masaru, Fujita, Hideaki, Sato, Hironori, Tokunaga, Kenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868573/
https://www.ncbi.nlm.nih.gov/pubmed/24367644
http://dx.doi.org/10.1371/journal.pone.0084228