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Exposure to Inflammatory Cytokines IL-1β and TNFα Induces Compromise and Death of Astrocytes; Implications for Chronic Neuroinflammation

BACKGROUND: Astrocytes have critical roles in the human CNS in health and disease. They provide trophic support to neurons and are innate-immune cells with keys roles during states-of-inflammation. In addition, they have integral functions associated with maintaining the integrity of the blood-brain...

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Detalles Bibliográficos
Autores principales: van Kralingen, Christa, Kho, Dan Ting, Costa, Jessica, Angel, Catherine Elizabeth, Graham, E. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868583/
https://www.ncbi.nlm.nih.gov/pubmed/24367648
http://dx.doi.org/10.1371/journal.pone.0084269