Suberoylanilide Hydroxamic Acid Induces Hypersensitivity to Radiation Therapy in Acute Myelogenous Leukemia Cells Expressing Constitutively Active FLT3 Mutants

Histone deacetylase inhibitors (HDIs) have shown promise as candidate radiosensitizer for many types of cancers. However, the mechanisms of action are not well understood, and whether they could have clinical impact on radiotherapy for leukemia is unclear. In this study, we demonstrate that suberoyl...

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Detalles Bibliográficos
Autores principales: Chen, Xufeng, Radany, Eric H., Wong, Patty, Ma, Shenglin, Wu, Kan, Wang, Bing, Wong, Jeffrey Y. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868602/
https://www.ncbi.nlm.nih.gov/pubmed/24367670
http://dx.doi.org/10.1371/journal.pone.0084515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868602/
https://www.ncbi.nlm.nih.gov/pubmed/24367670
http://dx.doi.org/10.1371/journal.pone.0084515

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