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Effect on HIV-1 Gene Expression, Tat-Vpr Interaction and Cell Apoptosis by Natural Variants of HIV-1 Tat Exon 1 and Vpr from Northern India

BACKGROUND: Since HIV-1 Tat and Vpr genes are involved in promoter transactivation, apoptosis, etc, we carried out studies to find out nature and extent of natural variation in the two genes from seropositive patients from Northern India and determined their functional implications. METHODS: HIV-1 t...

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Detalles Bibliográficos
Autores principales: Lata, Sneh, Ronsard, Larance, Sood, Vikas, Dar, Sajad A., Ramachandran, Vishnampettai G., Das, Shukla, Banerjea, Akhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868622/
https://www.ncbi.nlm.nih.gov/pubmed/24367500
http://dx.doi.org/10.1371/journal.pone.0082128