Combinatorial PD-1 Blockade and CD137 Activation Has Therapeutic Efficacy in Murine Cancer Models and Synergizes with Cisplatin

There is an urgent need for improved therapy for advanced ovarian carcinoma, which may be met by administering immune-modulatory monoclonal antibodies (mAbs) to generate a tumor-destructive immune response. Using the ID8 mouse ovarian cancer model, we investigated the therapeutic efficacy of various...

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Detalles Bibliográficos
Autores principales: Wei, Huafeng, Zhao, Likun, Li, Wei, Fan, Kexing, Qian, Weizhu, Hou, Sheng, Wang, Hao, Dai, Min, Hellstrom, Ingegerd, Hellstrom, Karl Erik, Guo, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868659/
https://www.ncbi.nlm.nih.gov/pubmed/24367702
http://dx.doi.org/10.1371/journal.pone.0084927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868659/
https://www.ncbi.nlm.nih.gov/pubmed/24367702
http://dx.doi.org/10.1371/journal.pone.0084927

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