New vehicles allow detergent-free mass spectrometry of membrane protein complexes

The rapid growth in the study of membrane protein complexes in lipid microenvironments prompts new methods for their characterization. Here we develop mass spectrometry as a method for studying membrane proteins incorporated into amphipols, bicelles and nanodiscs. We compare these detergent-free veh...

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Detalles Bibliográficos
Autores principales: Hopper, Jonathan T.S., Yu, Yvonne Ting-Chun, Li, Dianfan, Raymond, Alison, Bostock, Mark, Liko, Idlir, Mikhailov, Victor, Laganowsky, Arthur, Benesch, Justin L.P., Caffrey, Martin, Nietlispach, Daniel, Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868940/
https://www.ncbi.nlm.nih.gov/pubmed/24122040
http://dx.doi.org/10.1038/nmeth.2691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868940/
https://www.ncbi.nlm.nih.gov/pubmed/24122040
http://dx.doi.org/10.1038/nmeth.2691

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