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Annexin V-TRAIL fusion protein is a more sensitive and potent apoptotic inducer for cancer therapy

The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent, which kills cancer cells selectively, while leaving normal cells unharmed. However, the emerging resistance of tumor cells and patients to TRAIL-induced apoptosis limits its further applicati...

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Detalles Bibliográficos
Autores principales: Qiu, Fan, Hu, Minjin, Tang, Bo, Liu, Xiufeng, Zhuang, Hongqin, Yang, Jie, Hua, Zi-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868960/
https://www.ncbi.nlm.nih.gov/pubmed/24356445
http://dx.doi.org/10.1038/srep03565