Single cell Hi-C reveals cell-to-cell variability in chromosome structure

Large-scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and DNA replication and repair. Genomic techniques based on chromosome conformation capture assess contacts for millions of loci simultaneously, but do so by averaging chromosome conformat...

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Detalles Bibliográficos
Autores principales: Nagano, Takashi, Lubling, Yaniv, Stevens, Tim J., Schoenfelder, Stefan, Yaffe, Eitan, Dean, Wendy, Laue, Ernest D., Tanay, Amos, Fraser, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869051/
https://www.ncbi.nlm.nih.gov/pubmed/24067610
http://dx.doi.org/10.1038/nature12593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869051/
https://www.ncbi.nlm.nih.gov/pubmed/24067610
http://dx.doi.org/10.1038/nature12593

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