Assessing the effect of dynamics on the closed-loop protein-folding hypothesis

The closed-loop (loop-n-lock) hypothesis of protein folding suggests that loops of about 25 residues, closed through interactions between the loop ends (locks), play an important role in protein structure. Coarse-grain elastic network simulations, and examination of loop lengths in a diverse set of...

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Detalles Bibliográficos
Autores principales: Chintapalli, Sree V., Illingworth, Christopher J. R., Upton, Graham J. G., Sacquin-Mora, Sophie, Reeves, Philip J., Mohammedali, Hani S., Reynolds, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869168/
https://www.ncbi.nlm.nih.gov/pubmed/24258160
http://dx.doi.org/10.1098/rsif.2013.0935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869168/
https://www.ncbi.nlm.nih.gov/pubmed/24258160
http://dx.doi.org/10.1098/rsif.2013.0935

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