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SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expression

Survivin, a member of the IAP (inhibitor of apoptosis) gene family, is overexpressed in virtually all human cancers and is functionally involved in the inhibition of apoptosis, regulation of cell proliferation, metastasis and resistance to therapy. Because of its upregulation in malignancy, survivin...

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Detalles Bibliográficos
Autores principales: Felix, Silke, Sandjo, Louis P, Opatz, Till, Erkel, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869210/
https://www.ncbi.nlm.nih.gov/pubmed/24367452
http://dx.doi.org/10.3762/bjoc.9.323