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An efficient method for the construction of polysubstituted 4-pyridones via self-condensation of β-keto amides mediated by P(2)O(5) and catalyzed by zinc bromide
A self-condensation cyclization reaction mediated by phosphorus pentoxide (P(2)O(5)) and catalyzed by zinc bromide (ZnBr(2)) is presented for the synthesis of polysubstituted 4-pyridones and 2-pyridones from β-keto amides. A variety of β-keto amides are used in this approach, and a wide range of fun...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869214/ https://www.ncbi.nlm.nih.gov/pubmed/24367433 http://dx.doi.org/10.3762/bjoc.9.304 |