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Involvement of RhoH GTPase in the Development of B-Cell Chronic Lymphocytic Leukemia

RhoH is a hematopoietic-specific, GTPase-deficient member of the Rho GTPase family that functions as a regulator of thymocyte development and T-cell receptor signaling by facilitating localization of ZAP70 to the immunological synapse. Here we investigated the role of RhoH in the B-cell lineage. B-c...

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Detalles Bibliográficos
Autores principales: Sanchez-Aguilera, Abel, Rattmann, Ina, Drew, David Z., Müller, Lars U.W., Summey, Victoria, Lucas, David M., Byrd, John C., Croce, Carlo M., Gu, Yi, Cancelas, Jose A., Johnston, Patrick, Moritz, Thomas, Williams, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869226/
https://www.ncbi.nlm.nih.gov/pubmed/19847197
http://dx.doi.org/10.1038/leu.2009.217