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Involvement of RhoH GTPase in the Development of B-Cell Chronic Lymphocytic Leukemia
RhoH is a hematopoietic-specific, GTPase-deficient member of the Rho GTPase family that functions as a regulator of thymocyte development and T-cell receptor signaling by facilitating localization of ZAP70 to the immunological synapse. Here we investigated the role of RhoH in the B-cell lineage. B-c...
Autores principales: | Sanchez-Aguilera, Abel, Rattmann, Ina, Drew, David Z., Müller, Lars U.W., Summey, Victoria, Lucas, David M., Byrd, John C., Croce, Carlo M., Gu, Yi, Cancelas, Jose A., Johnston, Patrick, Moritz, Thomas, Williams, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869226/ https://www.ncbi.nlm.nih.gov/pubmed/19847197 http://dx.doi.org/10.1038/leu.2009.217 |
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