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Efficient synthesis of dihydropyrimidinones via a three-component Biginelli-type reaction of urea, alkylaldehyde and arylaldehyde

A one-pot three-component synthesis of dihydropyrimidinones via a molecular iodine-catalyzed tandem reaction of simple readily available mono-substituted urea, alkylaldehyde, and arylaldehyde has been developed. The reaction proceeds with high chemo- and regioselectivity to give highly diverse dihyd...

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Detalles Bibliográficos
Autores principales: Qu, Haijun, Li, Xuejian, Mo, Fan, Lin, Xufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869270/
https://www.ncbi.nlm.nih.gov/pubmed/24367449
http://dx.doi.org/10.3762/bjoc.9.320