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Why do proteins aggregate? “Intrinsically insoluble proteins” and “dark mediators” revealed by studies on “insoluble proteins” solubilized in pure water
In 2008, I reviewed and proposed a model for our discovery in 2005 that unrefoldable and insoluble proteins could in fact be solubilized in unsalted water. Since then, this discovery has offered us and other groups a powerful tool to characterize insoluble proteins, and we have further addressed sev...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869494/ https://www.ncbi.nlm.nih.gov/pubmed/24555050 http://dx.doi.org/10.12688/f1000research.2-94.v1 |