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Characterization of early pathogenesis in the SOD1(G93A) mouse model of ALS: part I, background and methods

Charcot first described amyotrophic lateral sclerosis (ALS) in 1869; however, its causes remain largely unknown and effective, long-term treatment strategies are not available. The first mouse model of ALS was developed after the identification of mutations in the superoxide dismutase 1 (SOD1) gene...

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Detalles Bibliográficos
Autores principales: Vinsant, Sharon, Mansfield, Carol, Jimenez-Moreno, Ramon, Del Gaizo Moore, Victoria, Yoshikawa, Masaaki, Hampton, Thomas G, Prevette, David, Caress, James, Oppenheim, Ronald W, Milligan, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869677/
https://www.ncbi.nlm.nih.gov/pubmed/24381807
http://dx.doi.org/10.1002/brb3.143