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Characterization of early pathogenesis in the SOD1(G93A) mouse model of ALS: part I, background and methods
Charcot first described amyotrophic lateral sclerosis (ALS) in 1869; however, its causes remain largely unknown and effective, long-term treatment strategies are not available. The first mouse model of ALS was developed after the identification of mutations in the superoxide dismutase 1 (SOD1) gene...
Autores principales: | Vinsant, Sharon, Mansfield, Carol, Jimenez-Moreno, Ramon, Del Gaizo Moore, Victoria, Yoshikawa, Masaaki, Hampton, Thomas G, Prevette, David, Caress, James, Oppenheim, Ronald W, Milligan, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Inc
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869677/ https://www.ncbi.nlm.nih.gov/pubmed/24381807 http://dx.doi.org/10.1002/brb3.143 |
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