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Nicotine Deteriorates the Osteogenic Differentiation of Periodontal Ligament Stem Cells through α7 Nicotinic Acetylcholine Receptor Regulating wnt Pathway

AIMS: Cigarette smoking is one of the high risk factors of adult chronic periodontitis and nicotine is the well established toxic substance in cigarette. However, the mechanism of nicotine induced periodontitis is still unknown. Here we studied whether nicotine impaired the osteogenic differentiatio...

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Detalles Bibliográficos
Autores principales: Zhou, Zhifei, Li, Bei, Dong, Zhiwei, Liu, Fen, Zhang, Yu, Yu, Yang, Shang, Fengqing, Wu, Lizheng, Wang, Xiaojing, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869757/
https://www.ncbi.nlm.nih.gov/pubmed/24376645
http://dx.doi.org/10.1371/journal.pone.0083102