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CHIP Regulates AKT/FoxO/Bim Signaling in MCF7 and MCF10A Cells
A number of studies have shown that apoptosis resistance can be observed in multiple human tumors; however the detailed mechanism remains unclear. In the present study, we demonstrated that the abnormal overexpression of the C terminus of Hsc70-interacting protein (CHIP) induced apoptosis resistance...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869759/ https://www.ncbi.nlm.nih.gov/pubmed/24376685 http://dx.doi.org/10.1371/journal.pone.0083312 |