The Frequency and Clinical Significance of IDH1 Mutations in Chinese Acute Myeloid Leukemia Patients

OBJECTIVE: Mutations in the gene encoding isocitrate dehydrogenease 1 (IDH1) occur in various hematopoietic tumors including acute myeloid leukemia (AML), myeloproliferative neoplasms and myelodysplastic syndromes. IDH1 mutations are significant in both diagnosis and prognosis of these conditions. I...

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Detalles Bibliográficos
Autores principales: Guan, Lixun, Gao, Li, Wang, Lili, Li, Meng, Yin, Yue, Yu, Li, Gao, Chunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869765/
https://www.ncbi.nlm.nih.gov/pubmed/24376688
http://dx.doi.org/10.1371/journal.pone.0083334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869765/
https://www.ncbi.nlm.nih.gov/pubmed/24376688
http://dx.doi.org/10.1371/journal.pone.0083334

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