Cargando…

PARP-14 Binds Specific DNA Sequences to Promote Th2 Cell Gene Expression

PARP-14, a member of the poly ADP-ribose polymerase super family, promotes T helper cell 2 (Th2) differentiation by regulating interleukin-4 (IL-4) and STAT6-dependent transcription. Yet, whether PARP-14 globally impacts gene regulation has not been determined. In this report, using an RNA pol II Ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riley, Jonathan P., Kulkarni, Aishwarya, Mehrotra, Purvi, Koh, Byunghee, Perumal, Narayanan B., Kaplan, Mark H., Goenka, Shreevrat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869773/ https://www.ncbi.nlm.nih.gov/pubmed/24376650 http://dx.doi.org/10.1371/journal.pone.0083127

Ejemplares similares

Mono-ADP-ribosylation by PARP10 and PARP14 in genome stability
por: Dhoonmoon, Ashna, et al.
Publicado: (2023)

PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities
por: Đukić, Nina, et al.
Publicado: (2023)

Single-molecule force spectroscopy reveals binding and bridging dynamics of PARP1 and PARP2 at DNA double-strand breaks
por: Bell, Nicholas A. W., et al.
Publicado: (2023)

PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling
por: van Beek, Lotte, et al.
Publicado: (2021)

In Vivo Function of an Interleukin 2 Receptor β Chain (IL-2Rβ)/IL-4Rα Cytokine Receptor Chimera Potentiates Allergic Airway Disease
por: Youn, Jeehee, et al.
Publicado: (1998)

CCCTC-binding Factor Activates PARP-1 Affecting DNA Methylation Machinery
por: Guastafierro, Tiziana, et al.
Publicado: (2008)

Research Progress on PARP14 as a Drug Target
por: Qin, Wei, et al.
Publicado: (2019)

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation
por: Iwata, Hiroshi, et al.
Publicado: (2016)

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites
por: Lin, Xiaohui, et al.
Publicado: (2022)

Clinical PARP inhibitors allosterically induce PARP2 retention on DNA
por: Langelier, Marie-France, et al.
Publicado: (2023)

How ligands regulate the binding of PARP1 with DNA: Deciphering the mechanism at the molecular level
por: Wang, Kai, et al.
Publicado: (2023)

SPINDOC binds PARP1 to facilitate PARylation
por: Yang, Fen, et al.
Publicado: (2021)

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks
por: Krietsch, Jana, et al.
Publicado: (2012)

Sequence homology between human PARP14 and the SARS-CoV-2 ADP ribose 1’-phosphatase
por: Webb, Thomas E., et al.
Publicado: (2020)

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation
por: Zarkovic, Gabriella, et al.
Publicado: (2018)

A two-step mechanism governing PARP1-DNA retention by PARP inhibitors
por: Xue, Huijun, et al.
Publicado: (2022)

Effects of PARP-1 Deficiency on Th1 and Th2 Cell Differentiation
por: Sambucci, M., et al.
Publicado: (2013)

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2
por: Moustakim, Moses, et al.
Publicado: (2018)

PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation
por: Torretta, Archimede, et al.
Publicado: (2023)

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1
por: Langelier, Marie-France, et al.
Publicado: (2014)

The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1
por: Dhoonmoon, Ashna, et al.
Publicado: (2022)

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo
por: Shao, Zhengping, et al.
Publicado: (2020)

Molecular Mechanism of Selective Binding of NMS-P118 to PARP-1 and PARP-2: A Computational Perspective
por: Wang, Ran, et al.
Publicado: (2020)

DNA-dependent SUMO modification of PARP-1()
por: Zilio, Nicola, et al.
Publicado: (2013)

Dna is a New Target of Parp3
por: Belousova, E. A., et al.
Publicado: (2018)

PARP14: A key ADP-ribosylating protein in host–virus interactions?
por: Parthasarathy, Srivatsan, et al.
Publicado: (2022)

PARP14 is a novel target in STAT6 mutant follicular lymphoma
por: Mentz, Michael, et al.
Publicado: (2022)

Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism
por: Mehrotra, Purvi, et al.
Publicado: (2015)

The HSF1–PARP13–PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis
por: Fujimoto, Mitsuaki, et al.
Publicado: (2017)

[(18)F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging
por: Guibbal, Florian, et al.
Publicado: (2020)

Taf2 mediates DNA binding of Taf14
por: Klein, Brianna J., et al.
Publicado: (2022)

14th International Conference on Intelligent Autonomous Systems
por: Chen, Weidong, et al.
Publicado: (2017)

PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response
por: Kim, Chiho, et al.
Publicado: (2020)

Inhibition of DNA damage repair by artificial activation of PARP with siDNA
por: Croset, Amelie, et al.
Publicado: (2013)

Visualization of a DNA-PK/PARP1 complex
por: Spagnolo, Laura, et al.
Publicado: (2012)

The role of PARP in DNA repair and its therapeutic exploitation
por: Javle, M, et al.
Publicado: (2011)

Functional Aspects of PARP1 in DNA Repair and Transcription
por: Ko, Hui Ling, et al.
Publicado: (2012)

PARP‐1 regulates DNA repair factor availability
por: Schiewer, Matthew J, et al.
Publicado: (2018)

TRLS-14. TARGETING REPLICATIVE STRESS IN BRAIN TUMORS BY COMBINING ATR AND PARP INHIBITION
por: Sarvode, Supriya, et al.
Publicado: (2023)

New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage
por: Gu, Zongying, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mcjrvr82g9tn88n4h62hinloi1