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New Orf Virus (Parapoxvirus) Recombinant Expressing H5 Hemagglutinin Protects Mice against H5N1 and H1N1 Influenza A Virus

Previously we demonstrated the versatile utility of the Parapoxvirus Orf virus (ORFV) as a vector platform for the development of potent recombinant vaccines. In this study we present the generation of new ORFV recombinants expressing the hemagglutinin (HA) or nucleoprotein (NP) of the highly pathog...

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Detalles Bibliográficos
Autores principales: Rohde, Jörg, Amann, Ralf, Rziha, Hanns-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869816/
https://www.ncbi.nlm.nih.gov/pubmed/24376753
http://dx.doi.org/10.1371/journal.pone.0083802