Expression of DNA Translesion Synthesis Polymerase η in Head and Neck Squamous Cell Cancer Predicts Resistance to Gemcitabine and Cisplatin-Based Chemotherapy

PURPOSE: The development of resistance against anticancer drugs has been a persistent clinical problem for the treatment of locally advanced malignancies in the head and neck mucosal derived squamous cell carcinoma (HNSCC). Recent evidence indicates that the DNA translesion synthesis (TLS) polymeras...

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Detalles Bibliográficos
Autores principales: Zhou, Wendi, Chen, Yih-wen, Liu, Xiyong, Chu, Peiguo, Loria, Sofia, Wang, Yafan, Yen, Yun, Chou, Kai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869838/
https://www.ncbi.nlm.nih.gov/pubmed/24376779
http://dx.doi.org/10.1371/journal.pone.0083978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869838/
https://www.ncbi.nlm.nih.gov/pubmed/24376779
http://dx.doi.org/10.1371/journal.pone.0083978

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