Silencing of Reversion-Inducing Cysteine-Rich Protein with Kazal Motifs Stimulates Hyperplastic Phenotypes through Activation of Epidermal Growth Factor Receptor and Hypoxia-Inducible Factor-2α

Reversion-inducing cysteine-rich protein with Kazal motifs (RECK, a tumor suppressor) is down-regulated by the oncogenic signals and hypoxia, but the biological function of RECK in early tumorigenic hyperplastic phenotypes is largely unknown. Knockdown of RECK by small interfering RNA (siRECK) or hy...

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Detalles Bibliográficos
Autores principales: Lee, You Mie, Lee, Sun-Hee, Lee, Kheun Byeol, Nguyen, Minh Phuong, Lee, Min-Young, Park, Gyu Hwan, Kwon, Mi Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869844/
https://www.ncbi.nlm.nih.gov/pubmed/24376819
http://dx.doi.org/10.1371/journal.pone.0084520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869844/
https://www.ncbi.nlm.nih.gov/pubmed/24376819
http://dx.doi.org/10.1371/journal.pone.0084520

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