Wound Healing Improvement with PHD-2 Silenced Fibroblasts in Diabetic Mice

BACKGROUND: Hypoxia-inducible factor 1α is the central regulator of the hypoxia-induced response which results in the up-regulation of angiogenic factors. Its activity is under precise regulation of prolyl-hydroxylase domain 2. We hypothesized that PHD2 silenced fibroblasts would increase the expres...

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Detalles Bibliográficos
Autores principales: Zhang, Xiongliang, Yan, Xiaoyu, Cheng, Liang, Dai, Jiezhi, Wang, Chunyang, Han, Pei, Chai, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869847/
https://www.ncbi.nlm.nih.gov/pubmed/24376825
http://dx.doi.org/10.1371/journal.pone.0084548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869847/
https://www.ncbi.nlm.nih.gov/pubmed/24376825
http://dx.doi.org/10.1371/journal.pone.0084548

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