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Potential Reduction of Contralateral Second Breast-Cancer Risks by Prophylactic Mammary Irradiation: Validation in a Breast-Cancer-Prone Mouse Model

BACKGROUND: Long-term breast-cancer survivors have a highly elevated risk (1 in 6 at 20 years) of contralateral second breast cancer. This high risk is associated with the presence of multiple pre-malignant cell clones in the contralateral breast at the time of primary breast cancer diagnosis. Mecha...

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Detalles Bibliográficos
Autores principales: Shuryak, Igor, Smilenov, Lubomir B., Kleiman, Norman J., Brenner, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869887/
https://www.ncbi.nlm.nih.gov/pubmed/24376895
http://dx.doi.org/10.1371/journal.pone.0085795