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Microcystin-LR Induced Reactive Oxygen Species Mediate Cytoskeletal Disruption and Apoptosis of Hepatocytes in Cyprinus carpio L.

Microcystins (MCs) are a group of cyclic hepatotoxic peptides produced by cyanobacteria. Microcystin-LR (MC-LR) contains Leucine (L) and Arginine (R) in the variable positions, and is one of the most common and potently toxic peptides. MC-LR can inhibit protein phosphatase type 1 and type 2A (PP1 an...

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Detalles Bibliográficos
Autores principales: Jiang, Jinlin, Shan, Zhengjun, Xu, Weili, Wang, Xiaorong, Zhou, Junying, Kong, Deyang, Xu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869903/
https://www.ncbi.nlm.nih.gov/pubmed/24376844
http://dx.doi.org/10.1371/journal.pone.0084768