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Deposition of Doxorubicin in Rats following Administration of Three Newly Synthesized Doxorubicin Conjugates

We previously reported the synthesis of three DOX conjugates that represented different targeting vehicles and showed them to have antitumor activity both in vitro and in vivo. However, the relationships between the pharmacokinetics of these DOX conjugates and their chemical structures were not char...

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Detalles Bibliográficos
Autores principales: Huan, Menglei, Tian, Shuang, Cui, Han, Zhang, Bangle, Su, Dan, Wang, Jieping, Li, Kangchu, Cao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870082/
https://www.ncbi.nlm.nih.gov/pubmed/24381947
http://dx.doi.org/10.1155/2013/926584