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Lipid A’s Structure Mediates Neisseria gonorrhoeae Fitness during Experimental Infection of Mice and Men

Phosphoethanolamine (PEA) on Neisseria gonorrhoeae lipid A influences gonococcal inflammatory signaling and susceptibility to innate host defenses in in vitro models. Here, we evaluated the role of PEA-decorated gonococcal lipid A in competitive infections in female mice and in male volunteers. We i...

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Detalles Bibliográficos
Autores principales: Hobbs, Marcia M., Anderson, James E., Balthazar, Jacqueline T., Kandler, Justin L., Carlson, Russell W., Ganguly, Jhuma, Begum, Afrin A., Duncan, Joseph A., Lin, Jessica T., Sparling, P. Frederick, Jerse, Ann E., Shafer, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870242/
https://www.ncbi.nlm.nih.gov/pubmed/24255126
http://dx.doi.org/10.1128/mBio.00892-13