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cor, a Novel Carbon Monoxide Resistance Gene, Is Essential for Mycobacterium tuberculosis Pathogenesis

Tuberculosis, caused by Mycobacterium tuberculosis, remains a devastating human infectious disease, causing two million deaths annually. We previously demonstrated that M. tuberculosis induces an enzyme, heme oxygenase (HO1), that produces carbon monoxide (CO) gas and that M. tuberculosis adapts its...

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Detalles Bibliográficos
Autores principales: Zacharia, Vineetha M., Manzanillo, Paolo S., Nair, Vidhya R., Marciano, Denise K., Kinch, Lisa N., Grishin, Nick V., Cox, Jeffery S., Shiloh, Michael U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870250/
https://www.ncbi.nlm.nih.gov/pubmed/24255121
http://dx.doi.org/10.1128/mBio.00721-13