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Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex

The shortening of the poly(A) tail of cytoplasmic mRNA (deadenylation) is a pivotal step in the regulation of gene expression in eukaryotic cells. Deadenylation impacts on both regulated mRNA decay as well as the rate of mRNA translation. An important enzyme complex involved in poly(A) shortening is...

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Detalles Bibliográficos
Autores principales: Winkler, G. Sebastiaan, Balacco, Dario L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870282/
https://www.ncbi.nlm.nih.gov/pubmed/24391663
http://dx.doi.org/10.3389/fgene.2013.00296