DNMT1-interacting RNAs block gene specific DNA methylation

DNA methylation was described almost a century ago. However, the rules governing its establishment and maintenance remain elusive. Here, we present data demonstrating that active transcription regulates levels of genomic methylation. We identified a novel RNA arising from the CEBPA gene locus critic...

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Detalles Bibliográficos
Autores principales: Di Ruscio, Annalisa, Ebralidze, Alexander K., Benoukraf, Touati, Amabile, Giovanni, Goff, Loyal A., Terragni, Joylon, Figueroa, Maria Eugenia, De Figureido Pontes, Lorena Lobo, Alberich-Jorda, Meritxell, Zhang, Pu, Wu, Mengchu, D’Alò, Francesco, Melnick, Ari, Leone, Giuseppe, Ebralidze, Konstantin K., Pradhan, Sriharsa, Rinn, John L., Tenen, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870304/
https://www.ncbi.nlm.nih.gov/pubmed/24107992
http://dx.doi.org/10.1038/nature12598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870304/
https://www.ncbi.nlm.nih.gov/pubmed/24107992
http://dx.doi.org/10.1038/nature12598

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