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Mibefradil reduces blood glucose concentration in db/db mice
OBJECTIVE: Numerous recent studies suggest that abnormal intracellular calcium concentration ([Ca(2+)](i)) is a common defect in diabetic animal models and patients. Abnormal calcium handling is an important mechanism in the defective pancreatic β-cell function in type 2 diabetes. T-type Ca(2+) chan...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870312/ https://www.ncbi.nlm.nih.gov/pubmed/24473561 http://dx.doi.org/10.6061/clinics/2014(01)09 |