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Mathematical Model of Naive T Cell Division and Survival IL-7 Thresholds

We develop a mathematical model of the peripheral naive T cell population to study the change in human naive T cell numbers from birth to adulthood, incorporating thymic output and the availability of interleukin-7 (IL-7). The model is formulated as three ordinary differential equations: two describ...

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Detalles Bibliográficos
Autores principales: Reynolds, Joseph, Coles, Mark, Lythe, Grant, Molina-París, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870322/
https://www.ncbi.nlm.nih.gov/pubmed/24391638
http://dx.doi.org/10.3389/fimmu.2013.00434