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Mathematical Model of Naive T Cell Division and Survival IL-7 Thresholds
We develop a mathematical model of the peripheral naive T cell population to study the change in human naive T cell numbers from birth to adulthood, incorporating thymic output and the availability of interleukin-7 (IL-7). The model is formulated as three ordinary differential equations: two describ...
Autores principales: | Reynolds, Joseph, Coles, Mark, Lythe, Grant, Molina-París, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870322/ https://www.ncbi.nlm.nih.gov/pubmed/24391638 http://dx.doi.org/10.3389/fimmu.2013.00434 |
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