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TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine

The regulatory cytokine tumor necrosis factor (TNF) exerts its effects through two receptors: TNFR1 and TNFR2. Defects in TNFR2 signaling are evident in a variety of autoimmune diseases. One new treatment strategy for autoimmune disease is selective destruction of autoreactive T cells by administrat...

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Detalles Bibliográficos
Autores principales: Faustman, Denise L., Davis, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870411/
https://www.ncbi.nlm.nih.gov/pubmed/24391650
http://dx.doi.org/10.3389/fimmu.2013.00478