A Novel Paramagnetic Relaxation Enhancement Tag for Nucleic Acids: A Tool to Study Structure and Dynamics of RNA

[Image: see text] In this work, we present a novel 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO) radical phosphoramidite building block, which can be attached to the 5′-terminus of nucleic acids. To investigate the paramagnetic relaxation enhancement (PRE) emanating from this radical center, we incor...

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Detalles Bibliográficos
Autores principales: Wunderlich, Christoph H., Huber, Roland G., Spitzer, Romana, Liedl, Klaus R., Kloiber, Karin, Kreutz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870906/
https://www.ncbi.nlm.nih.gov/pubmed/24053726
http://dx.doi.org/10.1021/cb400589q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870906/
https://www.ncbi.nlm.nih.gov/pubmed/24053726
http://dx.doi.org/10.1021/cb400589q

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