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The HDAC Inhibitor TSA Ameliorates a Zebrafish Model of Duchenne Muscular Dystrophy

Zebrafish are an excellent model for Duchenne muscular dystrophy. In particular, zebrafish provide a system for rapid, easy, and low-cost screening of small molecules that can ameliorate muscle damage in dystrophic larvae. Here we identify an optimal anti-sense morpholino cocktail that robustly knoc...

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Detalles Bibliográficos
Autores principales: Johnson, Nathan M., Farr, Gist H., Maves, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870918/
https://www.ncbi.nlm.nih.gov/pubmed/24459606
http://dx.doi.org/10.1371/currents.md.8273cf41db10e2d15dd3ab827cb4b027