Cargando…
AGG/CCT interruptions affect nucleosome formation and positioning of healthy-length CGG/CCG triplet repeats
BACKGROUND: Fragile X Syndrome (FXS), the most common inherited form of mental retardation, is caused by expansion of a CGG/CCG repeat tract in the 5′-untranslated region of the fragile X mental retardation (FMR1) gene, which changes the functional organization of the gene from euchromatin to hetero...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870987/ https://www.ncbi.nlm.nih.gov/pubmed/24261641 http://dx.doi.org/10.1186/1471-2091-14-33 |