Cargando…

AGG/CCT interruptions affect nucleosome formation and positioning of healthy-length CGG/CCG triplet repeats

BACKGROUND: Fragile X Syndrome (FXS), the most common inherited form of mental retardation, is caused by expansion of a CGG/CCG repeat tract in the 5′-untranslated region of the fragile X mental retardation (FMR1) gene, which changes the functional organization of the gene from euchromatin to hetero...

Descripción completa

Detalles Bibliográficos
Autores principales: Volle, Catherine B, Delaney, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870987/
https://www.ncbi.nlm.nih.gov/pubmed/24261641
http://dx.doi.org/10.1186/1471-2091-14-33