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AGG/CCT interruptions affect nucleosome formation and positioning of healthy-length CGG/CCG triplet repeats
BACKGROUND: Fragile X Syndrome (FXS), the most common inherited form of mental retardation, is caused by expansion of a CGG/CCG repeat tract in the 5′-untranslated region of the fragile X mental retardation (FMR1) gene, which changes the functional organization of the gene from euchromatin to hetero...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870987/ https://www.ncbi.nlm.nih.gov/pubmed/24261641 http://dx.doi.org/10.1186/1471-2091-14-33 |