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Amyloid β peptide-mediated neurotoxicity is attenuated by the proliferating microglia more potently than by the quiescent phenotype

BACKGROUND: The specific role of microglia on Aβ-mediated neurotoxicity is difficult to assign in vivo due to their complicated environment in the brain. Therefore, most of the current microglia-related studies employed the isolated microglia. However, the previous in vitro studies have suggested ei...

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Detalles Bibliográficos
Autores principales: Tsay, Huey-Jen, Huang, Yung-Cheng, Huang, Fong-Lee, Chen, Chia-Ping, Tsai, Yu-Chun, Wang, Ying-Hsiu, Wu, Mine-Fong, Chiang, Feng-Yi, Shiao, Young-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870991/
https://www.ncbi.nlm.nih.gov/pubmed/24152138
http://dx.doi.org/10.1186/1423-0127-20-78