Cargando…

Amyloid β peptide-mediated neurotoxicity is attenuated by the proliferating microglia more potently than by the quiescent phenotype

BACKGROUND: The specific role of microglia on Aβ-mediated neurotoxicity is difficult to assign in vivo due to their complicated environment in the brain. Therefore, most of the current microglia-related studies employed the isolated microglia. However, the previous in vitro studies have suggested ei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsay, Huey-Jen, Huang, Yung-Cheng, Huang, Fong-Lee, Chen, Chia-Ping, Tsai, Yu-Chun, Wang, Ying-Hsiu, Wu, Mine-Fong, Chiang, Feng-Yi, Shiao, Young-Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870991/ https://www.ncbi.nlm.nih.gov/pubmed/24152138 http://dx.doi.org/10.1186/1423-0127-20-78

Ejemplares similares

Cudrania cochinchinensis attenuates amyloid β protein-mediated microglial activation and promotes glia-related clearance of amyloid β protein
por: Wang, Chung-Jen, et al.
Publicado: (2013)

The Components of Flemingia macrophylla Attenuate Amyloid β-Protein Accumulation by Regulating Amyloid β-Protein Metabolic Pathway
por: Lin, Yun-Lian, et al.
Publicado: (2012)

Lithospermic acid attenuates 1-methyl-4-phenylpyridine-induced neurotoxicity by blocking neuronal apoptotic and neuroinflammatory pathways
por: Lin, Yun-Lian, et al.
Publicado: (2015)

Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice
por: Shie, Feng-Shiun, et al.
Publicado: (2015)

Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid
por: Tzeng, Tsai-Teng, et al.
Publicado: (2013)

Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid Deposition in Metabolically Stressed APPswe/PS1dE9 Mice
por: Huang, Yung-Cheng, et al.
Publicado: (2017)

Cysteine-rich domain of scavenger receptor Al modulates the efficacy of surface targeting and mediates internalization of oligomeric beta amyloid
por: Tsay, Huey-Jen
Publicado: (2013)

Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO
por: Tsay, Huey-Jen, et al.
Publicado: (2016)

Quiescent Fibroblasts Are More Active in Mounting Robust Inflammatory Responses Than Proliferative Fibroblasts
por: Chen, Bo-Rui, et al.
Publicado: (2012)

Amyloid β Dodecamer Disrupts the Neuronal Membrane More Strongly than the Mature Fibril: Understanding the Role of Oligomers in Neurotoxicity
por: Nguyen, Hoang Linh, et al.
Publicado: (2022)

Isorhamnetin Attenuated the Release of Interleukin-6 from β-Amyloid-Activated Microglia and Mitigated Interleukin-6-Mediated Neurotoxicity
por: Wei, Pei-Cih, et al.
Publicado: (2022)

Cysteine-rich domain of scavenger receptor AI modulates the efficacy of surface targeting and mediates oligomeric Aβ internalization
por: Huang, Fong-Lee, et al.
Publicado: (2013)

Methamphetamine neurotoxicity, microglia, and neuroinflammation
por: Shaerzadeh, Fatemeh, et al.
Publicado: (2018)

Quiescent Human Mesenchymal Stem Cells Are More Resistant to Heat Stress than Cycling Cells
por: Alekseenko, L. L., et al.
Publicado: (2018)

Brain Cells Release Calreticulin That Attracts and Activates Microglia, and Inhibits Amyloid Beta Aggregation and Neurotoxicity
por: Reid, Kyle M., et al.
Publicado: (2022)

TGF-β1 blockade of microglial chemotaxis toward Aβ aggregates involves SMAD signaling and down-regulation of CCL5
por: Huang, Wei-Chao, et al.
Publicado: (2010)

EK100 and Antrodin C Improve Brain Amyloid Pathology in APP/PS1 Transgenic Mice by Promoting Microglial and Perivascular Clearance Pathways
por: Tsay, Huey-Jen, et al.
Publicado: (2021)

Parecoxib Reduced Postsurgical Pain and Facilitated Movement More Than Patient Controlled Analgesia
por: Chiu, Szu-Ching, et al.
Publicado: (2022)

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
por: Zhang, Jiasheng, et al.
Publicado: (2020)

Are genotoxic carcinogens more potent than nongenotoxic carcinogens?
por: Parodi, S, et al.
Publicado: (1991)

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP
por: Yang, Xiaoxia, et al.
Publicado: (2018)

More than shingles
por: Neild, G. H., et al.
Publicado: (2012)

Amyloid precursor protein: more than just neurodegeneration
por: Pimplikar, Sanjay W, et al.
Publicado: (2011)

More than meets the eye: The role of microglia in healthy and diseased retina
por: Murenu, Elisa, et al.
Publicado: (2022)

Is Articaine More Potent than Mepivacaine for Use in Oral Surgery?
por: Gazal, Giath
Publicado: (2018)

Features of Microglia and Neuroinflammation Relevant to Environmental Exposure and Neurotoxicity
por: Kraft, Andrew D., et al.
Publicado: (2011)

Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity
por: Kirkley, Kelly S., et al.
Publicado: (2017)

Neuroprotective effects of statins against amyloid β-induced neurotoxicity
por: Li, Hsin-Hua, et al.
Publicado: (2018)

Combined Programmed Intermittent Bolus and Patient-Controlled Bolus Is a More Favorable Setting for Epidural Pain Relief Than Continuous Infusion
por: Liu, Shih-Kai, et al.
Publicado: (2023)

Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates
por: Samart, Nuttaporn, et al.
Publicado: (2018)

Coronatine is more potent than jasmonates in regulating Arabidopsis circadian clock
por: Gao, Min, et al.
Publicado: (2020)

Human cyclophilin 40 unravels neurotoxic amyloids
por: Baker, Jeremy D., et al.
Publicado: (2017)

Quantification and targeting of elusive neurotoxic amyloid oligomers
por: Bhatt, Nemil, et al.
Publicado: (2022)

Interleukin 13 on Microglia is Neurotoxic in Lipopolysaccharide-injected Striatum in vivo
por: Hong, Ah Reum, et al.
Publicado: (2022)

Waking up quiescent neural stem cells: Molecular mechanisms and implications in neurodevelopmental disorders
por: Ding, Wei Yung, et al.
Publicado: (2020)

Discovery of a Potent and Selective JNK3 Inhibitor with Neuroprotective Effect Against Amyloid β-Induced Neurotoxicity in Primary Rat Neurons
por: Jun, Joonhong, et al.
Publicado: (2021)

Nilotinib Is More Potent than Imatinib for Treating Plexiform Neurofibroma In Vitro and In Vivo
por: Wei, Jiang, et al.
Publicado: (2014)

Multimodal Imaging Characteristics of Quiescent Type 1 Neovascularization in Best Vitelliform Macular Dystrophy
por: Menteş, Jale, et al.
Publicado: (2021)

Pathogenic Microglia Orchestrate Neurotoxic Properties of Eomes-Expressing Helper T Cells
por: Zhang, Chenyang, et al.
Publicado: (2023)

Amyloid Oligomer Neurotoxicity, Calcium Dysregulation, and Lipid Rafts
por: Malchiodi-Albedi, Fiorella, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_2mr3sdk2289b857gqel3euispo