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DNA prime and peptide boost immunization protocol encoding the Toxoplasma gondii GRA4 induces strong protective immunity in BALB/c mice

BACKGROUND: Toxoplasma gondii is a widespread intracellular parasite, which infects most vertebrate animal hosts and causes zoonotic infection in humans. Vaccine strategy remains a promising method for the prevention and control of toxoplasmosis. T. gondii GRA4 protein has been identified as a poten...

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Detalles Bibliográficos
Autores principales: Meng, Min, Zhou, Aihua, Lu, Gang, Wang, Lin, Zhao, Guanghui, Han, Yali, Zhou, Huaiyu, Cong, Hua, Zhao, Qunli, Zhu, Xing-Quan, He, Shenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871000/
https://www.ncbi.nlm.nih.gov/pubmed/24148219
http://dx.doi.org/10.1186/1471-2334-13-494