Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells

BACKGROUND: Enhanced lipogenesis plays a critical role in cell senescence via induction of expression of the mature form of sterol regulatory element binding protein 1 (SREBP1), which contributes to an increase in organellar mass, one of the indicators of senescence. We investigated the molecular me...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, You-Mie, Song, Insun, Seo, Yong-Hak, Yoon, Gyesoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871034/
https://www.ncbi.nlm.nih.gov/pubmed/24396695
http://dx.doi.org/10.3803/EnM.2013.28.4.297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871034/
https://www.ncbi.nlm.nih.gov/pubmed/24396695
http://dx.doi.org/10.3803/EnM.2013.28.4.297

Ejemplares similares