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Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells

BACKGROUND: Enhanced lipogenesis plays a critical role in cell senescence via induction of expression of the mature form of sterol regulatory element binding protein 1 (SREBP1), which contributes to an increase in organellar mass, one of the indicators of senescence. We investigated the molecular me...

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Detalles Bibliográficos
Autores principales:	Kim, You-Mie, Song, Insun, Seo, Yong-Hak, Yoon, Gyesoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871034/ https://www.ncbi.nlm.nih.gov/pubmed/24396695 http://dx.doi.org/10.3803/EnM.2013.28.4.297

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