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Extracellular Acidosis Stimulates NHE2 Expression through Activation of Transcription Factor Egr-1 in the Intestinal Epithelial Cells
Na(+)/H(+) exchangers (NHEs) play important roles in regulating internal pH (pH(i)), cell volume and neutral Na(+) absorption in the human intestine. Earlier studies have shown that low extracellular pH (pH(e)) and metabolic acidosis increases the expression and function of NHE1-3 genes. However, tr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871166/ https://www.ncbi.nlm.nih.gov/pubmed/24376510 http://dx.doi.org/10.1371/journal.pone.0082023 |