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Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization

[Image: see text] Quantitative analysis of known drug–target interactions emerged in recent years as a useful approach for drug repurposing and assessing side effects. In the present study, we present a method that uses probabilistic matrix factorization (PMF) for this purpose, which is particularly...

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Detalles Bibliográficos
Autores principales: Cobanoglu, Murat Can, Liu, Chang, Hu, Feizhuo, Oltvai, Zoltán N., Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871285/
https://www.ncbi.nlm.nih.gov/pubmed/24289468
http://dx.doi.org/10.1021/ci400219z