Synergistic Mechanisms of DNA Demethylation during Transition to Ground-State Pluripotency

Pluripotent stem cells (PSCs) occupy a spectrum of reversible molecular states ranging from a naive ground-state in 2i, to metastable embryonic stem cells (ESCs) in serum, to lineage-primed epiblast stem cells (EpiSCs). To investigate the role of DNA methylation (5mC) across distinct pluripotent sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Hackett, Jamie A., Dietmann, Sabine, Murakami, Kazuhiro, Down, Thomas A., Leitch, Harry G., Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871394/
https://www.ncbi.nlm.nih.gov/pubmed/24371807
http://dx.doi.org/10.1016/j.stemcr.2013.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871394/
https://www.ncbi.nlm.nih.gov/pubmed/24371807
http://dx.doi.org/10.1016/j.stemcr.2013.11.010

Ejemplares similares