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Global Indiscriminate Methylation in Cell-Specific Gene Promoters following Reprogramming into Human Induced Pluripotent Stem Cells

Molecular reprogramming of somatic cells into human induced pluripotent stem cells (iPSCs) is accompanied by extensive changes in gene expression patterns and epigenetic marks. To better understand the link between gene expression and DNA methylation, we have profiled human somatic cells from differ...

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Detalles Bibliográficos
Autores principales: Nissenbaum, Jonathan, Bar-Nur, Ori, Ben-David, Eyal, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871396/
https://www.ncbi.nlm.nih.gov/pubmed/24371806
http://dx.doi.org/10.1016/j.stemcr.2013.11.007